Maybe to give a slight buff (maybe +10-20%) to walking or manipulation or something, add workout rooms where colonists can exercise. If they stay at a research bench or something all the time, maybe give a debuff (-10-20%) to walking speed or something unless they exercise. People who go hunting often may not need it as much, but if a colonist spends days sitting in front of a research table may develop cramps and other injuries by just doing nothing.
Shameless self-promotion. My thread about physical fitness and meta skills, it already discussed these things.
https://ludeon.com/forums/index.php?topic=20381.0