I haven't used it recently, but in the past Mediafire has done some pretty nasty stuff IMO. I've had a 50/50 chance to get a popup to very sketchy websites (including those fake antivirus / "You have a virus, don't close the page!" sites) when I had adblock plus installed. This was more than a year ago, but it made me very wary of them ever since.
I just tried it 6 times with uBlock Origin (refreshing the page in-between attempts) and I haven't had anything odd happen.
I just tried it 6 times with uBlock Origin (refreshing the page in-between attempts) and I haven't had anything odd happen.