300 mods? Is that all of them? 
Obviously people will have different views about what is an essential mod. I have a light load compared to many (it seems), because I like the base game and just want some quality of life. Others, maybe including you, will want mods that introduce new races, new weapons, new gear, new benches, everything under the sun -- that is what is so great about this game (well, one of them), games friendly to the modding community will thrive.
With that in mind, here are a few mods that I like and use
-Achtung
-Common Sense
-AllowTool
-Defensive Positions
-More Harvest Designators
-Rimworld Search Agency
-Work Tab
-Medical Tab
-Animal Tab
-Numbers
-Pick up and Haul
-Recipe Icons
-Don't block door mod
If you want to trim down from 300, try to figure out what you really need for gameplay or QoL purposes, then trim away some of the fat. It's a little hard to make recommendations without knowing how you like to play.

Obviously people will have different views about what is an essential mod. I have a light load compared to many (it seems), because I like the base game and just want some quality of life. Others, maybe including you, will want mods that introduce new races, new weapons, new gear, new benches, everything under the sun -- that is what is so great about this game (well, one of them), games friendly to the modding community will thrive.
With that in mind, here are a few mods that I like and use
-Achtung
-Common Sense
-AllowTool
-Defensive Positions
-More Harvest Designators
-Rimworld Search Agency
-Work Tab
-Medical Tab
-Animal Tab
-Numbers
-Pick up and Haul
-Recipe Icons
-Don't block door mod
If you want to trim down from 300, try to figure out what you really need for gameplay or QoL purposes, then trim away some of the fat. It's a little hard to make recommendations without knowing how you like to play.






Do you mean without any traps at all? I agree it's kinda cheesy since the enemies can't see them and we basically exploit pathfinding, but I don't really see how we would be able to handle 25-30 manhunting bears or rhinos if they get in our face either :-/ Or 150-200 tribal raiders without any way to thin out the pack a little bit before they all swarm us. I learnt the hard way that it can be a recipe for disaster, even when we have superior guns and armour.